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doi: 10.3389/fphar.2025.1543870 Received 12 December 2024 Accepted 25 March 2025 Published 14 May 2025 Volume 16 - 2025 Edited by Sabrina Petralla, Heidelberg University, Germany Reviewed by Yuan Wei, Jiangsu University, China Shameer Pillarisetti, University of Studies G

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As shown in Figure 2, when an intracellular iron overload occurs, excess iron promotes lipid peroxidation through ROS production and Fenton reaction, thus causing ferroptosis ( TFRC gene encoding TRF1 inhibits erastin-induced ferroptosis and prevents LIP accumulation, while HO-1 promotes ferroptosis by supplementing iron ( TRFC , FTH1 , and FTL (Sun et al., 2015)

Apply GHK-Cu first, let it absorb for 510 minutes, then apply retinol

The face wash consists of Glutathione and Vitamin E