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En el hgado, se cree que la acumulacin de lpidos deteriora la funcin mitocondrial, reduciendo as la oxidacin de los cidos grasos y aumentando la produccin de especies reactivas de oxgeno (ERO) que desencadenan la peroxidacin de lpidos, el dao del ADN, y la apoptosis

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doi: 10.1093/ageing/afy169 148

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It is supplied strictly for laboratory and research purposes

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doi: 10.1136/jim-2021-002051

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The regeneration of GSSG was slower in an ero1-1 mutant strain than in wild-type cells, and was faster in cells overexpressing Ero1 from a multicopy plasmid (Cuozzo & Kaiser, 1999)

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