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99 In intrinsically mediated pathways, Bcl-2 family members expressed in the mitochondria mainly induce apoptosis

MM was supported by the Associazione Italiana per la Ricerca sul Cancro (AIRC, IG 16719)

The influential analysis showed no change in the statistical significance or direction of the pooled effect (Before: WMD (95% CIs) = 11.24 (4.18, 18.30), p = 0.002

In addition to evaluating the risk of bias using the RoB 2 tool for RCTs and the ROBINS-I tool for non-randomized studies, we also assessed the overall quality of evidence using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) framework

Teprotumumab for non-inflammatory thyroid eye disease (TED): evidence for increased IGF-1R expression