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In addition, we implemented a rule-in approach (i.e., array approach) to estimate the impact of BMI on GLP-1RA effectiveness

(Wilding, 2022) However, it is possible to keep the weight off for good- it just requires consistent exercise, a healthy diet, and a thoughtful drug discontinuation plan

Hoogland J, Boel JA, de Bie RMA, Geskus RB, Schmand BA, Dalrymple-Alford JC, et al

It is a critical window for intervention

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Hunger may return because the body adapts after weight loss, the medication dose changes, treatment is stopped, stress increases, sleep worsens, activity changes, or old eating patterns return