FIGURE 6 5.1 In vitro tests Caudatin has been found to exhibit significant growth inhibition and induces apoptosis in a variety of cancer cell lines, such as hepatocellular carcinoma cell lines (HepG2 and SMMC-7721), breast carcinoma cell line (MCF-7) and lung carcinoma cell line (A549), with IC 50 values ranging from 3.11 to 44.68 mol/L ( 5.2 In vivo tests Studies conducted in animals such as rats and mice showed that caudatin did not cause significant side effects or systemic toxicity at therapeutic doses ( 6 Conclusion This review highlights the therapeutic viability of caudatin from structural optimization, pharmacological mechanism, and clinical implications, suggesting it as a multi-facilitive scaffold for drug discovery
For this reason, some people suggest that L-citrulline may be better for increasing arginine levels
Pesci A, Balbi B, Majori M, et al
Rashki et al., 2021)
A deficiency in B12 can increase susceptibility to infections and cause general fatigue
Glucagon Increases energy expenditure (boosted calorie burn), helps regulate blood sugar, and may enhance fat breakdown