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We found that LCN2 promotes intracellular iron accumulation, mitochondrial dysfunction, and lipid peroxidation through its receptor SLC22A17

The ensuing mechanistic study revealed that ebselen protected cells and mice models by lowering radiation-induced ROS production, followed by inhibition of lipid peroxidation, protein carbonylation, DNA damage, and ultimately apoptosis

Crack PJ, Taylor JM, Flentjar NJ, de Haan J, Hertzog P, Iannello RC et al

For the standard 10YO, they diluted it to 40%

Hooijberg JH, Pinedo HM, Vrasdonk C, Priebe W, Lankelma J, Broxterman HJ

"$63 million verdict in Children's Motrin case upheld"