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Therefore, it is urgent to study the molecular mechanisms of ferroptosis in the progression of aortic dissection and to explore treatment strategies for delaying its progression

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In response to inflammation and OxS, the activated HO-1 is a powerful down-regulator of pro-coagulant factors to prevent thrombotic events, endothelial injury from vascular inflammation, resolve FeRD and reset HMRD in COVID-19 and PASC patients 27,46

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