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Patients should always consult their healthcare provider before considering any changes to their treatment regimen and consider the potential side effects such as gastrointestinal issues

Metabolic dysfunction is what happens to lead to excess fat it could be decreased leptin (the satiety hormone), insulin resistance, or any number of hormonal imbalances

The medical record should highlight abnormal laboratory results, extreme vital sign variations, or severe gastrointestinal fluid losses

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They are biologically plausible, and some early studies are worth following

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