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To say something causes a reaction in science, we need strong evidence across multiple well-designed studies

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When the muscle beneath your injection site is contracted, the tissue is firmer, the needle meets more resistance, and nerve endings are more compressed

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Clinically, in patients with renal failure, acute kidney injury, dialysis and other pathological states of renal function deterioration, renal reabsorption function is impaired, resulting in a significantly lower serum free carnitine concentration than that in healthy people [255], and the metabolic profile of acylcarnitine also changes significantly [256]