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For example, berberine, often called natures Ozempic, has been shown to improve insulin sensitivity, reduce blood sugar levels, and potentially promote mild weight loss by activating an enzyme called AMPK, which regulates metabolism and energy use

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It plays a role in the production of the neurotransmitters serotonin and dopamine, as well, which is why it can strongly impact mood

But staying well hydrated genuinely matters on these drugs, because their most common side effects (nausea, vomiting, and diarrhea) can quietly drain your body of fluids

Sources: Astrup A, et al