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In the Phase 1 multiple-ascending dose (MAD) study, VK2735 achieved up to 8.2% mean weight loss at day 28 for the highest dose (100 mg)

Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium

The success of gene therapies in a number of rare diseases may now open the door to sustained benefit from gene therapy for more common diseases, like obesity and T2D, said Dr Mark Kay, Professor of Pediatrics and Genetics at Stanford University Medical School and Fractyl Health's Scientific Advisor

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Aging Cell 23, e14138

K., Choi, H., Swaminathan, B