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For the IV regimen, a loading dose of 150 mg/kg in 200 cc is given for 15 minutes, followed by 50 mg/kg in 500 cc over 4 hours and then 100 mg/kg in 1000 cc over 16 hours

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For antioxidants with few studies on protective effects against pollutants (vitamins C and E), studies of their effects on respiratory diseases, immune responses, and airway biology were included if links to air pollution exposure could be made

Heart failure events were not increased in EXAMINE [alogliptin, HR = 1.07 (124)], TECOS [sitagliptin