doi: 10.1016/j.arr.2023.102066
GLP-1s are not recommended while pregnant or breastfeeding
Dopamine/tyrosine hydroxylase neurons of the hypothalamic arcuate nucleus release GABA, communicate with dopaminergic and other arcuate neurons, and respond to dynorphin, met-enkephalin, and oxytocin
[4] [5] These symptoms result from delayed gastric emptying and direct effects on the gastrointestinal tract
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Shortening the interval to five days increases peak drug concentrations beyond the levels studied in clinical trials, raising nausea, vomiting, and gastrointestinal side effects without improving weight loss