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The HOGA1 gene is predominantly expressed in the kidney and the enzyme is localized to the mitochondria

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IgAN patients also present with increased concentrations of oxidized free cysteine in plasma, suggesting that the redox balance is disrupted in IgAN patients and that the oxidized cysteine level may be a useful prognostic risk marker for IgAN patients [276]

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(2006), but these authors observed a significant increase in NO concentration in the saliva of smokers immediately after smoking a cigarette, both in comparison with the control group and in the saliva of smokers before smoking a cigarette

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