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The FDA sent more than 50 warning letters to GLP-1 compounders and telehealth distributors in September 2025, followed by another 30 in March 2026, almost all focused on direct-to-consumer marketing

New combinations, such as GLP-1 agents paired with a mimic of the hormone amylin (which helps with fullness and lowering blood sugars), are showing significant promise and will be powerful tools in the toolbox

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The primary concern is not the safety of the medication itself, but rather the need for professional monitoring to manage the positive changes in your blood pressure and the potential for a slight increase in heart rate

In restricted states like Texas, Florida, and Pennsylvania, PMHNPs must have a collaborative agreement or protocol with a physician to prescribe