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the first step is conjugation of glutamic acid and cysteine, which is catalyzed by glutamate-cysteine ligase and generates -glutamyl-cysteine (-Glu-Cys) and the second step is catalyzed by glutathione synthase, which adds glycine to -Glu-Cys, forming glutathione

By protecting brain cells, glutathione may support better focus and "brain fog" reduction

The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon

The results showed that probiotic/prebiotic supplementation had no significant direct effect on TSH, free thyroxine and free triiodothyronine levels but significantly reduced thyrotrophin receptor antibody levels, revealing the potential value of probiotics and prebiotics in regulating autoimmune responses (Sanders et al., 2019)