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This is, to our knowledge, the first large multicenter study directly comparing GLP-1 receptor agonists and bariatric surgery in this population. Using the TriNetX research database, Patel and colleagues identified patients with BMI 30 kg/m 2 or greater who between 2016 and June 2025 had catheter ablation for AF and subsequently underwent bariatric surgery or initiated a GLP-1

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This helps reduce the risk of taking doses too close together

Some patients use GLP-1 medications indefinitely as a chronic disease management tool

This delivers approximately 0.2 mg of semaglutide, well below the therapeutic threshold but enough to begin receptor sensitization and assess initial tolerance