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Adding pathways adds mechanisms: tirzepatide outperforms semaglutide because two pathways work better than one, and retatrutide may outperform tirzepatide because three pathways address both caloric intake (appetite) and caloric output (energy expenditure) simultaneously

The safer takeaway is that GLP1 medications may affect some of the same systems involved in reward, appetite, metabolism, and self-regulation

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The research in regards to vitamin therapy is limited at this time, but I suspect more research will be performed and released in the upcoming years about the benefits of IV vitamin therapy