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[DOI] [PMC free article] [PubMed] [Google Scholar] Cao S., Ren X., Zhang Q., Chen E., Xu F., Chen J., et al

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27 In the early stage of T2D, impaired insulin synthesis and secretion plays a major role, with the stimuli reducing glucose-stimulated insulin secretion (GSIS), the basic function of cells

Thus, its protective effects overlap those of GPX1

Importantly, the treatment response was related to baseline homocysteine levels such that individuals with levels above 13 mol/L exhibited greater reductions in the rate of brain atrophy with B-vitamin supplementation than those with lower homocysteine levels

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