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Overexpression of drug efflux protein in drug-resistant tumor cells sharply decreases the concentration of drug uptake by tumor cells, which greatly limits the effect of chemotherapeutic drugs

The abbreviation in the name stands for body protection compound, part of a protein first isolated from human gastric juice

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While the exchange reaction for protein thiols finishes within 12 min (Gl et al

Good sources of vitamin B12 include: meat salmon and cod milk and other dairy products eggs For vegans, some alternatives are: yeast extract (including Marmite) fortified breakfast cereals and soy products Diet is not usually the cause of vitamin B12 deficiency in the UK - the most common one is pernicious anaemia

How the condition is evaluated and managed Clinicians typically confirm B12 status with blood work serum B12, and often methylmalonic acid (MMA) and homocysteine, which rise when B12 is functionally low