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[54] and, more recently, Nylander et al

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D., Hurst, J

It occurs endogenously in humans, where it has been identified in the hypothalamus, the limbic system, the pituitary, and even the gastrointestinal tract

The majority of primary liver cancers are hepatocellular carcinomas (HCC), accounting for 75% to 85% of cases ( In nonalcoholic fatty liver disease (NAFLD)-associated HCC, cancer cells show an elevated expression of N 6 -methyladenosine (m6A)-methyltransferase catalytic subunit (METTL3)