For GLP-1 users specifically, I prioritize movements that protect the muscle groups most vulnerable to atrophy during rapid weight loss: Lower body: Squats ( meaning any form of knee bend), deadlifts, lunges (glutes, quads, and hamstrings are the largest muscle groups and the biggest contributors to metabolic rate) Upper back and lats: Rows, pulldowns (postural muscles that deteriorate quickly without stimulus) Chest and shoulders: Presses, overhead work, flyes (functional pushing strength) Core: Planks, Pallof presses, loaded carries (spinal stability, injury prevention) Safety Note: If nausea is severe during early titration, reduce training volume (fewer sets per exercise) rather than eliminating sessions
Gagnon, J
This multidisciplinary approach helps you get the right treatment for your unique diagnosis as soon as possible
Cardiovascular outcomes and other key takeaways Overall, the authors found that all six OMMs were associated with significant improvements in weight loss compared to a placebo
Cilastatin, a DPEP1 inhibitor originally developed to protect antibiotics from breakdown, was associated with lower AKI rates in high-risk settings (including patients exposed to nephrotoxic antibiotics, chemotherapy, or contrast dyes)
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