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[44] After passing phase III clinical trials, Eli Lilly applied to the US Food and Drug Administration (FDA) for approval in 2021, with a priority review voucher

For saturation binding assays, cell lysates (100 L, 25 g of protein for HEK-293 cells and 1020 g of protein for INS-1E cells, quantified by the Bradford Assay) were incubated with the indicated concentrations of [ 3 H]RX821002 (90 min, room temperature)