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The other three participants dropped out during the intervention due to a major car accident, kidney failure, and gastric bypass surgery (see consort diagram in Supplementary Materials)

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The blind loop syndrome may produce deficiency of vitamin B 12 or folate

In HFD-fed mice, AT-SIRT3OE mitigated the secretion of inflammatory cytokines and chemokines from eWAT, thereby improving systemic inflammation and insulin sensitivity