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755 Mechanistically, SSAT1 overexpression increases ALOX15 expression and decreases the expression levels of GPX4 and SLC7A11 in primary cortical neurons, suggesting that SSAT1/ALOX15 axis activation may aggravate brain I/R injury by triggering ferroptosis in neurons

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Synaptic depression and short-term habituation are located in the sensory part of the mammalian startle pathway

They reflect the populations studied in clinical trials that demonstrated safety and efficacy