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Campbell JE, Drucker DJ

The types of substances GLP-1 users quit varied, with recreational prescription drugs topping the list at 38%

Though only a few years old, many previous analyses were outdated and did not reflect more recent findings, such as the cardiovascular benefits of these drugs

The Phase 3 safety database for orforglipron, encompassing several thousand participants treated for up to 72 weeks, provides reasonable but not definitive reassurance regarding pancreatic safety

This led to her study, cited below

Jensen et al., 2018) while a low level of GLP-1R-immunoreactivity was revealed in rat hippocampus ( in vivo electrophysiological recordings showed that juxtacellular application of the active fragment of GLP-1, GLP-1 (736) amide induces an increase and then a decrease of firing activity in the hippocampal CA1 neurons