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This manifested as an increase of intracellular ROS and a marked decrease of GSH

Clinicians should assess GLP-1 candidates for sleep quality, patterns, and duration using validated questionnaires like STOP-BANG [177], sleep initiation, sleep maintenance, or hypnotic drug use to assess insomnia [178] or questions about restless legs syndrome [179]

Multi-pharmacology of berberine in atherosclerosis and metabolic diseases: potential contribution of gut microbiota