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Melanotan 2 Receptor Activity Melanotan 2 shows broad activity across the melanocortin receptor family: MC1R activity: Strong agonist activity MC3R activity: Strong agonist activity MC4R activity: Strong agonist activity MC5R activity: Strong agonist activity This broad activity makes Melanotan 2 useful as a comprehensive melanocortin research tool but means observed effects cannot be attributed to any single receptor without additional mechanism deconvolution

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For example, in the case of t D-G1A, the interaction energy between each pose and the binding site was measured after ranking the four motifs

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