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GLP-1 Receptor Activation: Slows gastric emptying, reduces appetite, and lowers blood glucose levels

For adults with type 2 diabetes and diabetic nephropathy, it can reduce the risk of end-stage kidney disease

Injectable long-acting GLP-1s The following long-acting GLP-1 RAs are currently approved for use in the United States in liquid form for subcutaneous (under the skin) injection: Ozempic and Trulicity are injected once per week

Pfizer noted that the incidence of elevated liver enzymes with danuglipron was consistent with that observed in approved GLP-1 treatments

It should be avoided if strictures are suspected

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