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Rodent studies: Three preclinical studies investigated the effects of amino acid supplementation on ES-induced behavioral deficits

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This metabolite was discovered to mitigate ectopic lipid deposition in renal tubular cells, indicating the presence of a gut microbiota5-OPkidney axis (potentially mediated by Clostridium5-OPELD), which may serve as a novel intervention target (Steven et al., 2017

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