How often should Vitamin B12 injections be administered for maintenance therapy
This approval is based on the results of JETALS (The Japan Early-Stage Trial of Ultrahigh-Dose Methylcobalamin for ALS), multicenter, placebo-controlled, double-blind, randomized Phase III clinical trial in 130 patients with ALS, that was conducted as an investigator-initiated trial by a research team with Extraordinary Professor Ryuji Kaji (Principal Investigator), Tokushima University, and Professor Yuishin Izumi (Coordinating Investigator), the Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, and Professor Satoshi Kuwabara (Coordinating Investigator), the Department of Neurology, Chiba University Graduate School of Medicine
His podcast, Bulletproof Radio, has been downloaded more than 75 million times
Preclinical studies show promise for healing and neuroprotection, but human trials are ongoing or anecdotal
10.1016/s0928-4257(01)00040-7 83 Stancic-RokotovD.SlobodnjakZ.AralicaJ.AralicaG.PerovicD.StaresinicM.et al (2001b)
The placebo effect is also very real, especially with pain
