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Description

Some studies have suggested that GLP-1 analogues may have a positive impact on bone health and may increase bone density

These occur because the GLP-1 receptor is highly expressed in the gut and brainstem

PMID 22376048

Dose adjustment considerations : In some cases, delaying dose escalation or temporarily reverting to a previously tolerated dose may be necessary to improve tolerability while maintaining therapeutic benefit

Immunoblotting was conducted to assess the levels of total and cleaved caspase 3

Calabro FJ, Parr AC, Sydnor VJ, Hetherington H, Prasad KM, Ibrahim TS, et al