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Individuals with seizure disorders or psychiatric conditions should exercise caution, as high ammonia levels may exacerbate these conditions

Glucagon-Like Peptide-1 Receptor Agonists and Prevention of Stroke Systematic Review of Cardiovascular Outcome Trials With Meta-Analysis

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A 2023 systematic review and meta-analysis of 26 randomized controlled trials covering 1,721 participants found that hydrolyzed collagen supplementation produced statistically significant improvements in skin hydration and elasticity versus placebo

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This can complicate thyroid function interpretation and may necessitate dose adjustments in hypothyroid patients receiving levothyroxine