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2. Aceleracin de la quema de grasas

Unlike GLP-1, supraphysiologic GIP infusions do not amplify the late phase insulin response to glucose in patients with T2DM ( Native GLP-1 and GIP have limited pharmacologic value because of their short plasma half-life (17 min) ( Leveraging the Incretin Effect for the Treatment of T2DM Because of the apparent lack of beta-cell responsiveness to GIP in patients with poorly controlled T2DM, most therapeutic strategies have focused on enhancing the activity of GLP-1

That is the sensation that you get with GLP1 therapies and it is experienced by about 10-20% of people but the vast majority of these symptoms settle after around about 8-12 weeks in most people and if somebody were in a situation where they felt nauseated there is no reason that they need to escalate from 0.25mg up to 0.5mg until that nausea has settled

In the meantime, you don't have to wait

Elife 12 , e86015 (2023)

The starting dose of 2.5 mg is an initiation dose, not a therapeutic one