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Abbreviations used BST Baseline serum tryptase EDS Ehlers-Danlos syndrome GI Gastrointestinal HT Hereditary -tryptasemia MC Mast cell MCA MC activation MCAD MCA-related disorder MCAS MCA syndrome PGD2 Prostaglandin D 2 PGF2 Prostaglandin F 2 alpha POTS Postural orthostatic tachycardia syndrome SM Systemic mastocytosis REFERENCES 1.Akin C, Valent P, Metcalfe DD

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6.3 Combining ferroptosis inhibition with standard therapies Integrating ferroptosis-targeted therapies with existing ARDS interventions, such as corticosteroids, immunomodulators, or mechanical ventilation, presents both opportunities and challenges