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Many peptides are compounded medications and not FDA-approved for all indications

The half-life of tirzepatide extends approximately 5 days, meaning circadian timing produces minimal clinical differences in glucose control or weight loss outcomes when maintained weekly

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Knowing the full cost before committing including whether consultation, medication, supplies, shipping, and follow-up care are included or billed separately helps avoid unexpected charges

Separate CMS approval is not needed if coverage parameters are being updated to stay in step with this policy

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