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Unfortunately, due to many different nutritional, physiological, environmental and lifestyle factors Vitamin B12 deficiency is a common and growing problem today which may lead to anaemia and numerous unpleasant symptoms including mental fogginess, poor memory and concentration, fatigue, irritation, feelings of apathy and lack of motivation, mood swings, muscle weakness, or sleeping problems

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Cardiovascular outcomes trials for tirzepatide are ongoing, including SURMOUNT-MMO (NCT05386329), which is evaluating cardiovascular outcomes in patients with obesity and established cardiovascular disease

Subsequent work ought to standardize outcomes and reporting and use clinically relevant endpoints

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The NAD pointed out the lack of published human studies demonstrating that oral NAD+ supplementation elevates NAD+ levels, stating: So, whats the solution