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Furthermore, GIP(3-30)NH 2 has been used to demonstrate an uncoupling of the otherwise coupled processes of bone resorption and formation assessed by a decrease in CTX and a temporary increase in the bone formation marker procollagen type 1 amino terminal propertied (P1NP) in healthy individuals (100)

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NCT03574597 and NCT05556512)

The effects can remain for three to six months before needing to be repeated, but they are not permanent

Past reports have linked this drug class to worsening diabetic retinopathy and nonarteritic anterior ischemic optic neuropathy (NAION)

However, if youre undergoing medical treatment for cancer, epilepsy, or kidney dialysis, talk to your healthcare provider before beginning any folic acid supplementation