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Rotate Injection Sites (If Using Sub-Q/IM): To minimize discomfort or tissue irritation, switch between different sites (e.g., thighs, abdomen, upper arms)

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276 While AD has genetic causes, notably the apolipoprotein E4 (ApoE4) allele, which promotes the accumulation of A plaques through the MAPK signaling pathway, 277 the majority of cases are sporadic and strongly age-associated

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