Appetite Suppression (Central Nervous System) GLP-1 RAs can cross the blood-brain barrier or act on circumventricular organs to target specific brain regions, including the hypothalamus, hindbrain, and mesolimbic reward system (Zheng et al., 2024)
Additionally, Wegovy slows gastric emptying, which prolongs the sensation of fullness after meals and helps regulate blood glucose levels, although this effect diminishes with continued treatment
doi: 10.1016/J.BRAINRES.2015.09.035 26 ShahMVellaA
It is also used for metabolic syndrome such as prediabetes, weight loss, dyslipidemia due to its lipid-lowering effect, polycystic ovary syndrome, and other health conditions
Studies demonstrate that patients losing less than 5% body weight at early checkpoints rarely achieve clinically meaningful outcomes with continued treatment
Chief Data & Analytics Officer Craig Kurtzweil and Chief Medical Officer Dr