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Plasmodium falciparum possesses a classical glutaredoxin and a second, glutaredoxin-like protein with a PICOT homology domain

Some experts even call it an anti-ulcer peptide

Single dose vials also reduce the risk of contamination

The cleavage-resistant mutant NDUFS1 D255A decreases ROS formation and delays the loss of plasma membrane integrity (Ricci et al., 2004), suggesting cI inhibition as an accelerator of apoptosis

In both peptides, the N-terminal histidine sits in an enclosed pocket forming hydrophobic and hydrogen bond interactions with E364 6 .53 , E387 7 .42 , R310 5 .40 , Y241 3 .44 , W306 5 .36 , I313 5 .43 and Q234 3 .37 however, these interactions are more persistent with GLP-1, and this is likely linked to the stability of interactions of Glu9 and with residues at the base of the binding cavity (Supplemental Table 3, Supplemental Movie 1)

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