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To help reduce the risk of lactic acidosis while taking Metformin, make sure to take the medication with meals to minimize stomach discomfort

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In the SURMOUNT-1 trial, side effects included: Nausea (31.0%) Diarrhoea (23.0%) Constipation (17.0%) Vomiting (12.0%) Despite higher weight loss than semaglutide in some studies, tolerability varies by individual

Zhang, C., Sheng, J., Li, G., Zhao, L., Wang, Y., Yang, W., Yao, X., Sun, L., Zhang, Z., & Cui, R