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Antioxid Redox Signal 2008

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P-glycoprotein (P-gp or ABCB1), a member of a large family of ATP Binding Cassette (ABC) transporters, mediates the active efflux of anticancer drugs [4]

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Nanosystems have the potential for drug specificity and local delivery, but their biocompatibility, immunogenicity, and biodegradability are also key factors in avoiding adverse reactions such as inflammation [145, 146]