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Notice the problem at the 2.4mg dose

The rationale is smoother blood levels, fewer GI side effects from peak concentrations, and more consistent appetite suppression throughout the week

The trial demonstrated a 20% reduction in major adverse cardiovascular events, primarily driven by reduced non-fatal heart attacks and strokes

The larger volume gives you more room to add a second medication without exceeding syringe capacity

Most providers recommend injecting on a day when you can rest if nausea occurs

It's contraindicated in people with a history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, or pancreatitis