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doi: 10.1210/en.2008-1479

The additive insulinotropic effect of GIP combined with GLP-1 results from direct beta-cell stimulation and enhancement of alpha-to-beta cell paracrine communication, with GIP contributing substantially to postprandial insulin secretion [30,31]

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The NHS recommends that pharmacological weight management should always be part of a comprehensive programme including behavioural support, rather than a standalone intervention