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Supplementary Figure Legends Supplementary Figure 1: Effect of changes in cholesterol on GLP-1R agonist responses in vivo and in primary islets - contd

Enhancing GLP-1 signaling in older individuals could mitigate chronic inflammation, improve metabolic equilibrium, and support neuroprotection, collectively contributing to extended healthspan and potentially lifespan

Do not stop GLP-1 abruptly

At the same time, larger reviews that looked across multiple trials have found mixed results

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One in three Americans (32%) think the American government is adequately prepared to deal with another pandemic or widespread health crisis