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Both options are designed to support appetite control, food noise reduction, and metabolic weight management, but they differ in how they are taken, how consistently patients use them, how they fit into daily life, and how providers think about dose strategy

Cahalan SM, Lukacs V, Ranade SS, Chien S, Bandell M, Patapoutian A

We searched PubMed (MEDLINE), EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science from database inception to 31 October 2021 to identify eligible randomized controlled trials (RCTs)

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Higher concentrations may offer some stability advantages in certain formulations because the peptide-to-surface ratio is more favorable, but they can also increase the risk of aggregation if the formulation is not optimized for that concentration