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A review published in 2025 found that significant weight regain occurred after 8 weeks of stopping weight loss medication

This addresses the underlying metabolic disturbances that perpetuate gastrointestinal dysfunction, making it particularly suitable for patients with obesity-related gastrointestinal issues and offering a novel auxiliary option for clinical intervention

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The evidence base for "probiotics for GLP-1 constipation" is constructed by combining the mechanism of GLP-1 motility slowing with the general functional-constipation probiotic literature, which is heterogeneous and strain-specific

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The destruction of the feeding center in the lateral hypothalamus in animals leads to anorexia with subsequent cachexia