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Perhaps, due to rapid growth, tumour cells require need a lot of energy generated by oxidative phosphorylation, but they are inherently more likely to lead to enhanced reactive oxygen species (ROS) producing, resulting in the occurrence of ferroptosis, which is detrimental to their own growth

Robinson MD, McCarthy DJ, Smyth GK

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Small-scale clinical trials revealed that GLP-1 and GLP-1-based medicines may have positive effects on low-grade inflammation, blood pressure, cholesterol, and microcirculation ( Due to their various modes of action, which include vasodilation, natriuresis, glucose and weight control, and direct cardioprotective effects, GLP-1 receptor agonists have therapeutic potential for treatment of heart failure ( Obesity is a major cause of cardiovascular diseases

Treatment may require at least a few years, according to Lane