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Figures S4 and S5 show networks of routes of administration for secondary outcomes

The exact plan depends on how bad the deficiency is and the patients health

These protocols form the foundation for current therapeutic dosing recommendations

Eating four to five smaller meals throughout the day rather than two to three large ones is often better tolerated during the first several weeks

In fact, one study found that peoples bodies absorbed about 49% of a 1-mcg dose of cyanocobalamin, compared to 44% of the same dose of methylcobalamin ( Conversely, another study comparing the two forms reported that about three times as much cyanocobalamin was excreted through urine, indicating that methylcobalamin may be retained better within your body ( However, some research suggests that differences in bioavailability between the two forms may be insignificant and that absorption could be influenced by factors such as age and genetics ( Unfortunately, recent research directly comparing these two forms of vitamin B12 is limited

The most common are mild and temporary